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KMID : 1143420180110300974
Public Health Weekly Report
2018 Volume.11 No. 30 p.974 ~ p.978
Hepatitis B virus cohort studies worldwide
Kee Mee-Kyung

Shin Young-Hyun
Kim Ki-Soon
Ahn Sang-Hoon
Abstract
Hepatitis B virus is a major cause of liver diseases such as cirrhosis and hepatocellular carcinoma in Korea. Markedly for men, the death rate due to liver diseases in Korea is the highest among the OECD countries, especially in patients in their 40s who engage in many social activities. Other countries that have high prevalence of chronic viral hepatitis, such as Taiwan and Greece, have extensive epidemiological data on the prevalence and causes of chronic liver disease, based on large cohort studies. By using long-term follow-up results of large cohort studies, they have investigated the causes and risks of cirrhosis and hepatocellular carcinoma development and established guidelines for appropriate treatment, according to national circumstances. In 2015, the Korea Centers for Disease Control and Prevention established a hepatitis B cohort study in Korea to prevent hepatitis B virus infection and disease progression. Here, we introduce several cohorts, which have already been established in other countries. By sharing cohort experience with other countries, we expect to establish a Korean hepatitis B cohort for future investigations.
KEYWORD
Hepatitis B, Cohort study, Liver disease, Hepatocellular carcinoma, Chronic viral hepatitis
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